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. 2020 Dec 10;8:584206. doi: 10.3389/fcell.2020.584206

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Copyright © 2020 Roh, Go, Park, Kim and Park.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Resolvin D series biosynthetic pathway. DHA is converted into 17S-HpDHA by LO. 17S-HpDHA is further transformed into RvD1, RvD2, RvD3, RvD4, RvD5, and RvD6. DHA, docosahexaenoic acid; LO, lipoxygenase; RvD, resolvin D; 17-hydroperoxydocosahexaenoic acid.