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. 2020 Dec 10;8:608308. doi: 10.3389/fcell.2020.608308

TABLE 3.

Grading for morphology.

Morphology Change Under Optical Microscope Grade
I Annulus Fibrosus (AF) Normal texture and free of damage and distortion 1
The damaged and distortion area is less than 30% 2
The damaged and distortion area is more than 30% 3
II Boundary between AF and NP Normal 1
Micro disrupted 2
Medium or severe disrupted 3
III NP Cells Normal cells with large amounts of vacuoles 1
Cells and vacuoles decreased slightly 2
Cells decreased moderately or severely without vacuoles 3
IV NP Matrix Normal gel appearance 1
Slightly congealed 2
Moderate or severe condensation 3