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. 2020 Dec 10;11:521004. doi: 10.3389/fgene.2020.521004

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Copyright © 2020 Tang, Chen, Peng, Zhou, Jiang, Wang and Zhuang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Two cell lines (Eca109 and KYSE410) were selected for subsequent experiments due to their relatively high expression among the five candidate ESCC cell lines (KYSE150, KYSE410, KYSE30, Eca109, and TE-1). (B,C) si-LINC01614#1 and si-LINC01614#2 show significant knockdown efficiency. (D,E) Downregulation of LINC01614 expression inhibited the migration ability of ESCC cell lines (Eca109 and KYSE410). (F,G) Knockdown of LINC01614 expression reduced expression of N-cadherin and ZEB1 in Eca109 and KYSE410 cells. Data are the mean ± SD from three independent experiments. ***P < 0.001; ****P < 0.0001. NC, negative control.