Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Dec 10;8:596788. doi: 10.3389/fcell.2020.596788

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Cui, Fang, Duan, Xiang, Wang, Zhang, Zhai, Cui and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The effects of DHA, cisplatin, and their combination on cell viability and sphere and colony formation. (A) Growth curves of TE-1 cells after treatment with DHA, cisplatin (CDDP), and their combination. (B) Analysis of the combination of DHA and CDDP in TE-1 cells. The cells were treated by using various concentrations of DHA and CDDP, either alone or in a fixed ratio for 48 h. The combination index was analyzed using the Calcusyn program. (C) Representative images for sphere formation of ALDH + TE-1 cells after treatment with DHA, CDDP, and DHA + CDDP at designated concentrations for 24 h. (D) Bar graph of sphere formation efficiency of ALDH + TE-1 cells after treatment with DHA or/and CDDP. *P < 0.05, compared with DMSO treated group. (E) Representative images of colony formation of ALDH + TE-1 cells after treatment with DHA, CDDP and DHA + CDDP at designated concentrations for 24 h. (F) Bar graph of colony formation efficiency of ALDH + TE-1 cells after treatment with DHA or/and CDDP. *P < 0.05, compared with DMSO treated group.