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. 2020 Dec 10;8:597961. doi: 10.3389/fcell.2020.597961

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Copyright © 2020 Guo, Liu, Zhang, Johnson, Feng, Zhang, Wu, Chen, Fang, Xiao, Xiao, Persson and Zou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Receiver operating characteristic curves of the 14-Gene Panel, serum prostate-specific antigen (PSA) and Gleason score for diagnosis of higher-risk and lower-risk PCa. ROC curve of the 14-Gene Panel (A), PSA (B), and Gleason score (C) in the prospective PCa urine cohort (n = 202). ROC curve of the 14-Gene Panel (D), PSA (E), and Gleason score (F) in patients with Gleason scores 6 and 7 in the prospective PCa urine cohort (n = 132). ROC curve of the 14-Gene Panel (G) and PSA (H) in patients with Gleason score 7 in the prospective PCa urine cohort (n = 84). ROC curve of the 14-Gene Panel (I) and Gleason score (J) in the retrospective PCa urine cohort (n = 97).