TABLE 6.
Sensitivity, specificity, PPV, and NPV of 4-Gene-Panel and Gleason score for diagnosis of higher-risk and lower-risk PCa in a retrospective Pca urine cohort.
14-gene panel |
Gleason score |
|||||
Positive | Negative | Total | Positive | Negative | Total | |
Higher risk | 36 | 11 | 47 | 9 | 36 | 45 |
Lower risk | 7 | 43 | 50 | 0 | 44 | 44 |
Total | 43 | 54 | 97 | 9 | 80 | 89 |
Sensitivity (95% CI) | 76.60 (88.70–64.49)% | 20.00 (31.69–8.31)% | ||||
Specificity (95% CI) | 86.00 (95.62–76.38)% | 100 (100–100)% | ||||
PPV (95% CI) | 83.72 (94.76–72.69)% | 100 (100–100)% | ||||
NPV (95% CI) | 79.63 (90.37–68.89)% | 55.00 (65.90–44.10)% |