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. 2020 Dec 10;8:597961. doi: 10.3389/fcell.2020.597961

TABLE 6.

Sensitivity, specificity, PPV, and NPV of 4-Gene-Panel and Gleason score for diagnosis of higher-risk and lower-risk PCa in a retrospective Pca urine cohort.

14-gene panel
Gleason score
Positive Negative Total Positive Negative Total
Higher risk 36 11 47 9 36 45
Lower risk 7 43 50 0 44 44
Total 43 54 97 9 80 89
Sensitivity (95% CI) 76.60 (88.70–64.49)% 20.00 (31.69–8.31)%
Specificity (95% CI) 86.00 (95.62–76.38)% 100 (100–100)%
PPV (95% CI) 83.72 (94.76–72.69)% 100 (100–100)%
NPV (95% CI) 79.63 (90.37–68.89)% 55.00 (65.90–44.10)%