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. 2020 Dec 10;11:570015. doi: 10.3389/fphys.2020.570015

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Copyright © 2020 Buess, Van Muylem, Nonclercq and Haut.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Link between FEV₁ (in % of its reference value in healthy subjects) and PRM^SAD obtained with our model (black curve). The open diamonds represent the experimental data of Criner et al. (2019). (B) Relation between inspiration flow rate and pressure drop in the bronchial tree, calculated with the model, for three situations: healthy lungs (black curve), lungs with PRM^fSAD = 21% (orange curve), and lungs with PRM^fSAD = 35% (purple curve). The dashed curve presents the linear relation of Ferris et al. (1964).