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. 2020 Dec 10;11:536706. doi: 10.3389/fpsyt.2020.536706

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Copyright © 2020 Muller and Meyerhoff.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The degree of global integration of the nine eBRS regions at 1 month into abstinence ad 3 months later. eBRS regions with a positive GIC value are coded in orange – yellow (range 0–0.05) and eBRS regions with a negative GIC value are coded in blue – light blue (range 0–0.1). When compared with the controls and abstainers, relapsers showed over-integration (= positive GIC values) in almost all eBRS regions, while the eBRS in the two other groups was mostly disconnected (= negative GIC values) from the global across-community interaction.