Table 3.
The global integration coefficient of the extended brain reward system (eBRS) and its constituent brain regions for the controls (CON), relapsers (REL), and abstainers (ABS).
| Global Integration Coefficient | |||
|---|---|---|---|
| CON | REL | ABS | |
| eBRS at TP1 | −0.0364/−0.0441 (0.0432) | 0.0034/−0.0030 (0.0609) | −0.0551/−0.0728 (0.0959) |
| eBRS at TP2 | −0.0412/−0.0392 (0.0792) | −0.0137/−0.0108 (0.0552) | −0.0610/−0.0714 (0.1032) |
| Cortical regions of the eBRS at TP1 | −0.0348/−0.0489 (0.0415) | 0.0283/0.0038 (0.0685) | −0.0391/−0.0409 (0.0735) |
| Cortical regions of the eBRS at TP2 | −0.0578/−0.0677 (0.0711) | −0.0314/−0.0246 (0.0667) | −0.0461/−0.0432 (0.0528) |
| Dorsolateral prefrontal cortex at TP1 | −0.0084/−0.0076 (0.0812) | −0.0367/−0.0392 (0.0775) | −0.0116/−0.0211 (0.1472) |
| Dorsolateral prefrontal cortex at TP2 | −0.0252/−0.0409 (0.1429) | −0.0534/−0.0527 (0.1316) | 0.0065/0.0238 (0.1254) |
| Ventromedial prefrontal cortex at TP1 | −0.0968/−0.0992 (0.1256) | 0.0219/0.0328 (0.0953) | −0.1040/−0.1101 (0.1661) |
| Ventromedial prefrontal cortex at TP2 | −0.1219/−0.1210 (0.1358) | −0.0316/−0.0073 (0.1290) | −0.1352/−0.1019 (0.2291) |
| Orbital prefrontal cortex at TP1 | −0.0453/−0.0364 (0.0554) | 0.0059/−0.0213 (0.0979) | −0.0196/−0.0218 (0.1430) |
| Orbital prefrontal cortex at TP2 | −0.0549/−0.0331 (0.1225) | −0.057/−0.0600 (0.0533) | −0.0304/−0.0663 (0.1224) |
| Anterior insula at TP1 | −0.0414/−0.0471 (0.0798) | 0.0165/0.0055 (0.1132) | −0.0446/−0.0276 (0.14301) |
| Anterior insula at TP2 | −0.0717/−0.0637 (0.0641) | −0.0164/−0.0082 (0.1162) | −0.0763/−0.0607 (0.1161) |
| Temporal pole at TP1 | −0.0271/−0.0330 (0.0787) | 0.0064/−0.0180 (0.1467) | −0.01577/−0.0036 (0.1464) |
| Temporal pole at TP2 | −0.0154/−0.0019 (0.0607) | 0.0019/−0.0067 (0.0797) | 0.0046/−0.0018 (0.1522) |
| Subcortical regions of the eBRS at TP1 | −0.0272/−0.0237 (0.0590) | 0.0042/0.0132 (0.0903) | −0.0751/−0.0717 (0.1272) |
| Subcortical regions of the eBRS at TP2 | −0.0203/−0.0229 (0.0982) | 0.0083/−0.0062 (0.1073) | −0.0796/−0.0935 (0.1688) |
| Hippocampus at TP1 | −0.0240/−0.0232 (0.0755) | 0.0304/0.0229 (0.0942) | −0.0507/−0.0393 (0.1266) |
| Hippocampus at TP2 | −0.0131/−0.0006 (0.0977) | 0.0242/0.0264 (0.0835) | −0.0401/−0.0601 (0.1342) |
| Amygdala at TP1 | −0.0229/−0.0357 (0.1342) | −0.0159/−0.0392 (0.1562) | −0.0484/−0.0898 (0.1907) |
| Amygdala at TP2 | −0.0051/−0.0017 (0.1051) | −0.0191/−0.275 (0.1206) | −0.0455/−0.0789 (0.0709) |
| Anterior thalamus at TP1 | −0.0405/−0.0523 (0.1279) | −0.0401/−0.0549 (0.1663) | −0.1185/−0.1125 (0.1807) |
| Anterior thalamus at TP2 | −0.0476/−0.0650 (0.1563) | −0.0113/−0.0276 (0.1791) | −0.1242/−0.1407 (0.2403) |
| Nucleus accumbens at TP1 | −0.0215/−0.0356 (0.1435) | 0.0431/0.0797 (0.1507) | −0.0825/−0.1071 (0.2492) |
| Nucleus accumbens at TP2 | −0.0257/−0.0213 (0.1671) | 0.0395/0.0265 (0.1468) | −0.1085/−0.1358 (0.2829) |
The table lists the mean, the median and the interquartil distance (in brackets) of the group-specific GIC values at each timepoint. The eBRS and its constituent brain regions were relatively over-integrated in the REL at TP1, since the REL group has generally the highest GIC values of all three groups at TP1 with exception of the GIC values of the dorsolateral prefrontal cortex.