Table 4.
List of significant group differences in Global Integration Coefficient (GIC) and Within Centrality of the eBRS at 1 month (TP1) into treatment and at follow-up 3 months later (TP2).
| Global Integration Coefficient | Within Centrality | |||||
|---|---|---|---|---|---|---|
| CON vs. REL | CON vs. ABS | REL vs. ABS | CON vs. REL | CON vs. ABS | REL vs. ABS | |
| eBRS at TP1 | p = 0.0013 (r = 0.446)* | p = 0.0136 (r = 0.423) | p < 0.0001 (g = 1.276)* | – | p = 0.0002 (g = 1.449)* | |
| eBRS at TP2 | – | – | – | p = 0.0039 (g = 0.381)* | – | p < 0.0001 (g = 1.872)* |
| Cortical regions of the eBRS at TP1 | p = 0.0022 (r = 0.425)* | – | – | p = 0.0175 (g = 0.691) | – | – |
| Cortical regions of the eBRS at TP2 | – | – | – | – | – | – |
| Dorsolateral prefrontal cortex at TP1 | – | – | – | – | – | – |
| Dorsolateral prefrontal cortex at TP2 | – | – | – | p = 0.0246 (g = 0.763) | – | p = 0.0027 (g = 1.302)* |
| Ventromedial prefrontal cortex at TP1 | p < 0.0001 (r = 0.571)* | – | p = 0.0026 (r = 0.532)* | p < 0.0001 (g = 1.345)* | – | p = 0.0003 (g = 1.188)* |
| Ventromedial prefrontal cortex at TP2 | p = 0.0040 (r = 0.487) | – | p = 0.0242 (r = 0.460) | – | – | – |
| Orbital prefrontal cortex at TP1 | p = 0.0485 (r = 0.274) | – | – | – | – | p = 0.0409 (g = 0.776) |
| Orbital prefrontal cortex at TP2 | – | – | – | – | – | – |
| Anterior insula at TP1 | p = 0.0201 (r = 0.322) | – | – | – | – | – |
| Anterior insula at TP2 | p = 0.0451 (r = 0.339) | – | – | – | – | – |
| Temporal pole at TP1 | – | – | – | – | – | – |
| Temporal pole at TP2 | – | – | – | – | – | p = 0.0269 (g = 1.079) |
| Subcortical regions of the eBRS at TP1 | – | – | p = 0.009 (r = 0.448) | p < 0.0001 (g = 1.197)* | – | p < 0.0001 (g = 1.578)* |
| Subcortical regions of the eBRS at TP2 | – | – | p = 0.0207 (r = 0.472) | p = 0.0014 (g = 1.141)* | p = 0.0083 (g = 1.086)* | p < 0.0001 (g =2.307)* |
| Hippocampus at TP1 | p = 0.0103 (r = 0.356) | – | p = 0.0136 (r = 0.423) | – | – | – |
| Hippocampus at TP2 | – | – | – | – | p = 0.0054 (g = 1.075)* | p = 0.0027 (g = 1.321)* |
| Amygdala at TP1 | – | – | – | – | – | – |
| Amygdala at TP2 | – | – | – | – | – | p = 0.0278 (g = 0.936) |
| Anterior thalamus at TP1 | – | – | – | – | – | – |
| Anterior thalamus at TP2 | – | – | – | p = 0.0215 (g = 0.778) | – | p = 0.0494 (g = 0.753) |
| Nucleus accumbens at TP1 | p = 0.0109 (r = 0.353) | – | p = 0.0065 (r = 0.467)* | p < 0.0001 (g = 1.521)* | – | p < 0.0001 (g = 1.755)* |
| Nucleus accumbens at TP2 | – | – | p = 0.0242 (r = 0.458) | p < 0.0001 (g = 1.578)* | p = 0.004 (g = 1.191)* | p < 0.0001 (g = 2.747)* |
The results of the Wilcoxon rank sum tests used to test for group differences in the not-normally distributed GIC values and the corresponding effects sizes r (in brackets) computed following the formula of Rosenthal et al. (48) are listed on the left side of the table. The results of the Student t-tests used to test for group differences in the normally distributed Within Centrality and the corresponding effect sizes (Hodge's g) are listed on the right side of the table. Asteriks indicate p values that stay significant at q = 0.05 after Benjamini-Hochberg correction for multiple comparisons.