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. 2020 Dec 10;10:593989. doi: 10.3389/fonc.2020.593989

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Copyright © 2020 Zhou, Wei, Zhang, Yang and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pan-cancer RE neoantigen profile analysis of TCGA cohorts. (A) RE neoantigen distribution and expression of ADAR1 in 12 cancer types. (B) RE neoantigen and somatic neoantigen comparison of 12 cancer types. (C) Driver gene distribution of neoantigen in each cancer type. (D) Flowchart of how IFI30 was confirmed expressed and presented. (E) Correlations between RE neoantigen burden and somatic neoantigen burden, expression of CD8A/GZMA/PDCD1/ADAR1/ADAR2 and clinical covariates in 12 cancer types.