Figure 10.

En face analyses of aorta atherosclerotic lesions. (a) Representative images of atherosclerotic plaques in aortas of Ldlr^−/- mice fed with different diets. ORO stain was used to stain neutral lipids in atherosclerotic lesions. The sizes of atherosclerotic plaques were quantified en face and presented in % plaque size of total areas of (b) total vessel, (c) aortic arch, and (d) thoracic aorta respectively. Data are presented as mean ± SEM (n = 6). Significant differences are represented by: ∗p < 0.05; ∗∗p < 0.01 as compared to HFD group (one way ANOVA with Dunnett's test as post-hoc).