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. 2020 Dec 10;8:599389. doi: 10.3389/fcell.2020.599389

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Copyright © 2020 Wang, Gao, Zheng, Chen, Ma, Shen, Qu, Zhang, Gurney, O’Donnell and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The proteomics analysis of differentially expressed proteins in the hippocampus and frontal cortex samples. (A) Volcano plot of differentially expressed proteins in the hippocampus and frontal cortex after BPN14770 treatment (n = 8). Fold change >1.2 or <0.83, and P < 0.05 as the cut off values for differential protein quantification. (B) Venn diagram of hippocampus and frontal cortex differentially expressed proteins. (C) The biological processes of gene ontology (GO) enrichment analysis of the differentially expressed proteins in the hippocampus. (D) The biological processes of GO enrichment analysis of the differentially expressed proteins in the cortex.