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. 2020 Dec 22;4:2470547020980681. doi: 10.1177/2470547020980681

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© The Author(s) 2020

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Increased volume in right opercular IFG after ketamine administration. A, Before ketamine administration, both MDD and MDD/PTSD subjects showed significantly smaller volume in right opercular IFG compared to HC subjects. Besides, MDD subjects had a significantly smaller volume in left lateral OFC. B, After ketamine administration, there was no significant volume difference in right opercular IFG between HC, MDD, and MDD/PTSD groups. However, both MDD and MDD/PTSD groups showed a significantly smaller volume in left lateral OFC compared to HC. Asterisks indicates significance at p < 0.05.