Fig. 3.

Cellular functions of the nuclear pore complex. The nuclear pore complex and its multiple cellular functions: nucleocytoplasmic transport, regulation of gene expression and 3D genome architecture (Buchwalter et al., 2019; Raices and D'Angelo, 2017; Strambio-De-Castillia et al., 2010), chromatin organization (Kuhn and Capelson, 2019), DNA repair (Freudenreich and Su, 2016; Géli and Lisby, 2015), mRNA surveillance (Géli and Lisby, 2015), post-translational protein modifications (Texari and Stutz, 2015), cytoskeletal organization (Joseph and Dasso, 2008; Joseph et al., 2004), and cell cycle regulation (Chatel and Fahrenkrog, 2011; Imamoto and Funakoshi, 2012).