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Interrelationship of OA biomarkers. MMP-9, matrix metalloproteinase-9; OPN, osteopontin; ADAMTS4, a disintegrin and metalloproteinase with thrombospondin motifs 4; PRG4, proteoglycan 4; IL-1,interleukin-1; IL-6, interleukin-6; TNF-α, tumor necrosis factor alpha; CRP, C-reactive protein; THA, totalhip arthroplasty.
