The Mirtron Pathway Can Substitute for Abundant Endogenous miRNAs
(A) Schematic of the experimental strategy to test for miRNA sufficiency: a block in miRNA biogenesis at the Microprocessor level is bypassed by splicing during the process of mirtron biogenesis.
(B) Hatching rates of miR-35fam and miR-51fam mutant embryos with or without mirt-35 or mirt-51, respectively. Error bars represent the standard error of the proportion.
See also Figure S2.