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. 2021 Jan 15;279:609–616. doi: 10.1016/j.jad.2020.10.009

Table 2.

Incidence rates and hazard ratios for suicide by PTSD status.

Crude mortality rate1 Hazard ratios (95% CI)
Rate 95% CI Unadjusted Adjustment 12 Adjustment 23
Total 12•9 (12•6–13•2)
PTSD
No 12•6 (12•3–12•9) 1 1 1
Yes 53•9 (46•8–62•1) 4•28 (3•70–4•94) 5•36 (4•64–6•20) 2•16 (1•86–2•50)
Men 67•2 (53•1–85•1) 3•81 (3•00–4•83) 3•96 (3•12–5•03) 1•67 (1•31–2•12)
Women 48•5 (40•6–57•9) 6•85 (5•70–8•23) 6•74 (5•61–8•09) 2•61 (2•16–3•14)
LRT test Χ2 for interaction (df); p-value 15•3 (1); 0•0001 12•5 (1); 0•0004 8•8 (1); 0•003
Broadly-defined PTSD4
No 12•5 (12•2–12•8) 1 1 1
Yes 62•5 (55•3–70•6) 4•93 (4•35–5•58) 6•11 (5•38–6•93) 2•50 (2•19–2•84)
Men 89•3 (74–107•8) 5•01 (4•14–6•06) 5•14 (4•25–6•23) 2•23 (1•84–2•71)
Women 51•4 (43•8–60•3) 7•26 (6•14–8•58 7•10 (6•01–8•39) 2•74 (2•32–3•25)
LRT test Χ2 for interaction (df); p-value 8•3 (1); 0•004 6•3 (1); 0•01 2•6 (1); 0•11

LRT: likelihood ratio test; df: degrees of freedom; PTSD: post-traumatic stress disorder; 95% CI: 95% confidence intervals.

1 per 100,000 person-years.

2 Adjusted for current age, natal sex (except in stratified analyses), country of origin, population density and deprivation.

3 Adjusted for variables listed in Adjustment 1, previous major depression or anxiety disorders, bipolar disorder, non-affective psychotic disorder, previous non-fatal suicide attempts and parental history of severe mental illness.

4 See first sensitivity analysis for definition.