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. 2021 Jan 15;279:316–323. doi: 10.1016/j.jad.2020.10.026

Table 2.

Death by suicide hazard ratios for loneliness, living arrangements and perceived social support, in unadjusted and adjusted models for men and women in the UK Biobank study.

Model 1 Model 2 Model 3 Model 4 Model 5 Model 6
HR 95% (CI) HR 95% (CI) HR 95% (CI) HR 95% (CI) HR 95% (CI) HR 95% (CI)
Men
Living arrangements (Cohabitating)
Alone 3.57 (2.61 to 4.87)*** 2.72 (1.93 to 3.82)*** 2.35 (1.66 to 3.32)*** 2.16 (1.51 to 3.09)*** 2.14 (1.50 to 3.09)*** 2.02 (1.40 to 2.93)***
Non partner 2.91 (1.80 to 4.73)*** 2.11 (1.28 to 3.49)*** 1.94 (1.17 to 3.20)** 1.80 (1.08 to 3.00)* 1.81 (1.09 to 3.01)* 1.72 (1.03 to 2.88)*
Loneliness (No)
Yes 3.20 (2.35 to 4.36)*** 2.45 (1.77 to 3.40)*** 1.71 (1.22 to 2.41)** 1.43 (1.01 to 2.03)* 1.39 (0.97 to 1.99)+
Emotional support (daily)
2–4 times a week 1.89 (1.11 to 3.21)* 1.69 (0.99 to 2.88)+ 1.51 (0.88 to 2.57) 1.29 (0.75 to 2.21) 1.25 (0.73 to 2.15)
Once a week 2.50 (1.59 to 3.92)*** 2.21 (1.40 to 3.49)** 2.00 (1.26 to 3.15)** 1.62 (1.02 to 2.60)* 1.55 (0.97 to 2.49)+
Monthly 1.60 (0.98 to 2.64)+ 1.45 (0.88 to 2.40) 1.30 (0.78 to 2.14) 1.08 (0.65 to 1.80) 1.02 (0.61 to 1.71)
Never 1.86 (1.26 to 2.73)*** 1.60 (1.08 to 2.36)* 1.51 (1.02 to 2.22)* 1.25 (0.83 to 1.87) 1.17 (0.77 to 1.76)
Women
Living arrangements (Cohabitating)
Alone 1.58 (0.96 to 2.61)+ 1.51 (0.89 to 2.54) 1.21 (0.71 to 2.06) 1.24 (0.72 to 2.12) 1.23 (0.72 to 2.11) 1.25 (0.72 to 2.15)
Non partner 1.45 (0.76 to 2.79) 1.24 (0.63 to 2.43) 1.01 (0.51 to 1.99) 1.03 (0.52 to 2.04) 1.02 (0.52 to 2.02) 1.03 (0.52 to 2.05)
Loneliness (No)
Yes 1.49 (0.91 to 2.43) 1.42 (0.86 to 2.34) 0.92 (0.55 to 1.54) 0.89 (0.53 to 1.50) 0.92 (0.54 to 1.57)
Emotional support (daily)
2–4 times a week 1.33 (0.70 to 2..54) 1.25 (0.66 to 2.38) 1.08 (0.57 to 2.05) 1.04 (0.54 to 2.00) 1.05 (0.55 to 2.02)
Once a week 1.21 (0.64 to 2.29) 1.18 (0.62 to 2.24) 0.97 (0.51 to 1.84) 0.93 (0.49 to 1.79) 0.95 (0.49 to 1.82)
Monthly 0.78 (0.35 to 1.74) 0.78 (0.35 to 1.75) 0.66 (0.30 to 1.48) 0.65 (0.29 to 1.45) 0.66 (0.29 to 1.49)
Never 1.13 (0.57 to 2.25) 1.17 (0.58 to 2.34) 1.00 (0.50 to 2.02) 0.98 (0.49 to 1.98) 1.00 (0.49 to 2.06)

*** p ≤ 0.001, ** p ≤ 0.01, * p ≤ 0.05, + p ≤ 0.1.

Model 1 univariable cox regression, model 2 adjusts for socio-demographic factors (sex, age, ethnicity, employment status, deprivation and highest qualification, ever had same sex relationship), model 3 is model 2 plus adjusting for health measures (number physical morbidities, ever depressed, on psychotropic medication, BMI, alcohol consumption, smoking). Model 4 is model 3 plus mutual adjustment for loneliness and living arrangements. Model 5 is model 3 plus mutual adjustment for living arrangements and perceived social support. Model 6 is model 3 plus mutual adjustment for living arrangements, loneliness and perceived social support.