Anomalous origin of the RCA from the left sinus of Valsalva and interarterial course (A), causing ischemia during exercise and hypoperfusion of the inferior septal wall of the LV during rest angiographic CT acquisition (B), color-coded in blue-violet and “slit-like ostium” at CT and ICA (C,D). After surgical repair (E) no more chest pain and related ischemia were observed. RCA, right coronary artery; LV, left ventricle; ICA, invasive coronary angiography.