Table 4.

Dark Zone and Light Zone Locomotor Activity in Light-Dark Box (mean ± SEM). Dark Zone (Top): B6N mice had increased active time and decreased velocity compared to B6J mice, but no differences for distance traveled or rearing were found. Light Zone (Bottom): B6J mice exhibited increased active time, velocity and rears compared to B6N mice. Additionally, B6J mice traveled more distance compared to B6N mice in the T = 21 cycle in mice consuming regular chow. σ indicates a baseline strain difference and italics denotes significant pairwise comparison, at p < .05.

Genotype	Diet	T-cycle	Active Time (min) (σ)	Distance (cm)	Velocity (cm/s) (σ)	Rears
Dark Zone
B6J	RC	T = 24	3.71 ± 0.35	579.24 ± 52.72	3.06 ± 0.054	25.55 ± 6.16
B6J	HF	T = 24	3.52 ± 0.36	522.37 ± 59.61	2.78 ± 0.072	28.00 ± 5.75
B6J	RC	T = 21	3.88 ± 0.44	630.81 ± 86.27	3.07 ± 0.13	27.37 ± 7.12
B6J	HF	T = 21	3.90 ± 0.30	619.02 ± 46.66	3.00 ± 0.076	29.22 ± 5.78
B6N	RC	T = 24	3.96 ± 0.68	488.70 ± 65.61	2.47 ± 0.082	26.71 ± 6.38
B6N	HF	T = 24	4.40 ± 0.45	554.65 ± 70.35	2.37 ± 0.085	25.66 ± 6.71
B6N	RC	T = 21	5.35 ± 0.47	661.70 ± 64.28	2.50 ± 0.12	43.40 ± 6.22
B6N	HF	T = 21	4.38 ± 0.66	555.21 ± 67.92	2.51 ± 0.19	26.14 ± 8.80
Light Zone
B6J	RC	T = 24	4.91 ± 0.23	698.15 ± 31.76	2.97 ± 0.10	71.00 ± 5.86
B6J	HF	T = 24	4.88 ± 0.32	706.64 ± 32.01	2.84 ± 0.094	56.44 ± 4.04
B6J	RC	T = 21	4.91 ± 0.39	821.90 ± 18.81	3.19 ± 0.22	64.62 ± 10.01
B6J	HF	T = 21	4.53 ± 0.30	728.77 ± 40.16	3.15 ± 0.11	60.66 ± 6.14
B6N	RC	T = 24	4.79 ± 0.52	678.90 ± 99.26	2.77 ± 0.12	42.42 ± 10.62
B6N	HF	T = 24	3.96 ± 0.47	506.60 ± 61.44	2.64 ± 0.20	42.80 ± 3.93
B6N	RC	T = 21	3.59 ± 0.33	483.18 ± 58.32	2.74 ± 0.21	36.50 ± 7.28
B6N	HF	T = 21	3.84 ± 0.69	529.84 ± 105.94	2.66 ± 0.15	31.00 ± 9.81