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GW9508 prevented ox-LDL-induced cellular senescence in human aortic endothelial cells (HAECs). Cells were treated with ox-LDL (100 μg/mL) in the presence or absence of GW9508 (50 μM) for 7 days. The SA-β-Gal activity of HAECs was measured to determine cellular senescence (***, P < 0.0001 vs the vehicle group; ##, P < 0.001 vs the ox-LDL group).
