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GW9508 decreased ox-LDL-induced production of reactive oxygen species (ROS) in human aortic endothelial cells (HAECs). Cells were treated with ox-LDL (100 μg/mL) in the presence or absence of GW9508 (50 μM) for 24 h. Production of ROS was determined using dihydroethidium (DHE) staining (***, P < 0.0001 vs vehicle control; ##, P < 0.001 vs the ox-LDL group).
