Table 3.

Epithelial ovarian cancer-specific mortality and all-cause mortality according to change in smoking from prediagnosis to postdiagnosis in the NHS and NHSII

		Epithelial ovarian cancer-specific mortality		All-cause mortality
	Total cases, n	Deaths, n	HR (95% CI)	Deaths, n	HR (95% CI)
Never smoker	539	275	1.00 (ref)	336	1.00 (ref)
Former smoker	433	255	1.20 (1.01,1.43)	299	1.19 (1.01,1.40)
Quit smoking after diagnosis	43	22	0.84 (0.54,1.31)	28	0.91 (0.62,1.35)
Remained current smoker	99	60	1.40 (1.05,1.87)	74	1.43 (1.11,1.86)

Never smoker is defined as being a never smoker at both prediagnosis and postdiagnosis assessments; Former smoker is defined as being a former smoker at both assessments; Quit smoking after diagnosis is defined as being a current smoker before diagnosis and former smoker after diagnosis; Remained current smoker is defined as being a current smoker at both assessments. Models adjusted for age and calendar year at diagnosis, tumor histologic subtype, stage, prediagnosis body mass index (BMI, categorical), change of BMI (categorical) and nonsteroidal anti-inflammatory drug usage from prediagnosis to postdiagnosis and cohort. Due to the small sample size, participants who reported past smoking before diagnosis and current smoking after diagnosis were excluded (n = 2).

Abbreviations: CI, confidence interval; HR, hazard ratio; NHS, Nurses’ Health Study; NHSII, Nurses’ Health Study II.

Bold values indicate p < 0.05.