Table 4. Cyclocarbonylative Sonogashira Coupling Reactions of 4′-Hydroxy-3′-iodoaryls (1a–d) with Alkyl Alkynes (5a–e) Catalyzed by C1a.
Reaction conditions: C1 (1.0 mol %), 4′-hydroxy, 3′-iodoaryl (0.50 mmol), alkyl alkyne (0.60 mmol), Et2NH (1.0 mmol), DMF (2.5 mL), CO (100 psi), 110 °C, 24 h.
Isolated yield.