TABLE 2.
Change in BOLD response to food stimuli following 10‐day HCD and 10‐day fast
| Condition | ROI | Hemisphere | k (E) | x | y | z a | t |
Uncorrected p‐value b |
Peak‐level PFWE‐corr c |
Cohen's d’ |
|---|---|---|---|---|---|---|---|---|---|---|
| Pre‐HCD > Post‐HCD: High‐calorie > Low‐calorie | ||||||||||
| Hypothalamus | R | 5 | 0 | 2 | −8 | 3.83 | .004 | 0.069 | 0.39 | |
| Pre‐Fast > Post‐Fast: Food > Objects | ||||||||||
| DLPFC | L | 191 | −36 | 20 | 37 | 12.27 | <.001 | 0.049 | 2.07 | |
| Post‐Fast > Pre‐Fast: Food > Objects | ||||||||||
| Hypothalamus | R | 21 | 6 | −1 | −17 | 6.64 | .001 | 0.050 | 2.65 | |
| OFC | R | 361 | 30 | 20 | −26 | 12.81 | <.001 | 0.036 | 5.99 | |
| Insula | L | 55 | −39 | 5 | −14 | 13.86 | <.001 | 0.014 | 4.87 | |
a
Coordinates are presented in MNI space.
b
Voxel‐wise Z‐score significance level p < .05 uncorrected for multiple comparisons within a hypothesized ROI; ROIs listed represent regions of significantly activated clusters within the a priori hypothesized ROI.
c
FWE rate (family‐wise error rate) used for SVC (small volume correction): Peak‐level significance level (FWE‐corrected within the search volume of interest); p values for ROIs reaching p(FWE‐corrected)<0.05 are bolded.