Table 2.
First author | Posttreatment adverse effects |
---|---|
Beach[26] | Hypertrichosis (38.8%), fluid retention (5.5%), hypotensive symptoms (5.5%) |
Fiedler-Weiss[32] | Hypertrichosis (17.0%), fluid retention, occasional episodes of headaches, depression, or lethargy in women; occasional episodes of palpitations or tachycardia after ingestion of caffeine, alcohol, or decongestants* |
Jimenez-Caube[27] | Hypertrichosis (24.3%), lower-limb edema (4.8%), hair shredding (2.4%) |
Lueangarun[28] | Hypertrichosis (93%), pedal edema (10%), ECG abnormality, including premature ventricular contractions and T-wave change (10% of patients) |
Ramos[29] | Hypertrichosis (27.0%), edema of the limbs (4.0%) |
Perera[34] | Hypertrichosis (38.8%), transient postural dizziness (5.5%)†, lower-limb edema (2.7%) |
Sinclair[31] | Hypertrichosis (4%), urticaria (2%), hypotensive symptoms (2%) |
Tanaka[30] | Swelling (0.22%), dizziness (0.15%) |
Wambier[33] | Hypertrichosis (50.0%), acne (25.0%) |
*Study did not show quantitative data regarding most of adverse effect described, †Side effect resolved after continued treatment