Table 1.
Anthropometric and biochemical changes in diclofenac-induced acute kidney injury compared with control
| Parameters | Control (n=10) | AKI (n=10) | Differences | 95% CI | P |
|---|---|---|---|---|---|
| BMI (g/cm2) | 0.55±0.1 | 0.61±0.1 | 0.110 | 0.01–0.20 | 0.02* |
| CreSerum (mg/dL) | 0.88±0.1 | 1.92±0.2 | 1.040 | 0.89–1.18 | 0.001# |
| Blood urea (mg/dL) | 39.73±7.96 | 57.28±9.61 | 17.550 | 9.25–25.84 | 0.0001# |
| eGFR (ml/min/1.73) | 15.88±3.75 | 11.69±2.64 | −4.190 | −8.15–0.22 | 0.03* |
| KIM (pg/mL) | 88.68±12.39 | 122.78±18.45 | 34.100 | 19.33–48.86 | 0.0001# |
| NGAL (pg/mL) | 14.93±4.61 | 22.83±5.63 | 7.900 | 0.06–9.73 | 0.001# |
| MDA (ng/mL) | 240.52±11.72 | 298.61±16.72 | 58.090 | 44.52–71.65 | 0.0001# |
| SOD (pg/mL) | 45.78±9.69 | 22.78±7.56 | 23.000 | −31.16–14.83 | 0.0001# |
Data presented as mean±SD. *P<0.05, #P<0.01. BMI: Body mass index, eGFR: Estimated glomerular filtration rate, KIM-1: Kidney injury molecules, NGAL: Neutrophil gelatinase-associated lipocalin, MDA: Malondialdehyde, SOD: Superoxide dismutase, SD: Standard deviation, CreSerum: Serum creatinine, AKI: Acute kidney injury, CI: Confidence interval