Table 1.
Baseline demographics and treatment characteristics for the entire study population and per SIRI groups.
| Characteristic | All patients (N = 181) | SIRI ≥ 1.93 (N = 110) | SIRI < 1.93 (N = 71) | p value |
|---|---|---|---|---|
| Median age, y (range) | 60 (33–80) | 61 (33–79) | 59 (36–79) | 0.91 |
|
| ||||
| Age group, y (%) | ||||
| <70 years | 132 (72.9) | 81 (73.6) | 51 (71.8) | 0.87 |
| ≥70 years | 49 (27.1) | 29 (26.4) | 20 (28.2) | |
|
| ||||
| Gender, n (%) | ||||
| Male | 154 (85.0) | 91 (82.7) | 63 (88.7) | 0.39 |
| Female | 27 (15.0) | 19 (17.3) | 8 (11.3) | |
|
| ||||
| ECOG-PS, n (%) | ||||
| 0–1 | 141 (71.7) | 84 (76.4) | 57 (80.3) | 0.48 |
| 2 | 40 (28.3) | 26 (23.6) | 14 (19.7) | |
|
| ||||
| Smoking status, n (%) | ||||
| Ex-smoker | 174 (96.1) | 106 (96.3) | 68 (95.8) | 0.90 |
| Current smoker | 7 (3.9) | 4 (3.7) | 3 (4.2) | |
|
| ||||
| ∗ Anemia, n (%) | ||||
| Present | 109 (60.2) | 66 (60.0) | 43 (60.6) | 0.94 |
| Absent | 72 (39.8) | 44 (40.0) | 28 (39.4) | |
|
| ||||
| PCI, n (%) | ||||
| Yes | 139 (76.7) | 85 (77.3) | 54 (76.1) | 0.79 |
| No | 42 (23.3) | 25 (22.7) | 17 (23.9) | |
|
| ||||
| TRT scheme | ||||
| CFRT 54 Gy | 77 (42.6) | 47 (42.7) | 30 (42.3) | 0.86 |
| HFRT 45 Gy | 104 (57.4) | 63 (57.3) | 41 (57.7) | |
|
| ||||
| Treatment center | ||||
| Baskent Un. | 104 (57.4) | 63 (57.3) | 41 (57.7) | 0.74 |
| Mersin City Hospital | 56 (30.9) | 35 (31.8) | 21 (29.6) | |
| Suleyman Demirel Un. | 21 (11.7) | 12 (10.9) | 9 (12.7) | |
∗Anemia refers to any Hb <130 g/dL for males and Hb <120 g/dL for females. Abbreviations . SIRI: systemic immune-inflammation response index; ECOG-PS, Eastern Cooperative Oncology Group performance status; PCI: prophylactic cranial irradiation; CFRT: conventionally fractionated radiotherapy; HFRT: hyperfractionated radiotherapy; Gy: gray; Un.: university.