Skip to main content
. 2020 Dec;21(12):961–976. doi: 10.1631/jzus.B2000161

Fig. 3.

Fig. 3

Mechanisms of HPV E6 and E7 proteins in the development of HPV-associated cancers

E7 and E6 react with the tumor suppressor gene products pRb and p53 in host cell proteins, respectively, resulting in carcinogenesis. E2F: E2 factor; E6AP: E6-associated protein; HPV: human papillomavirus