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. 2020 Dec 11;10:527921. doi: 10.3389/fcimb.2020.527921

Table 1.

Nature of IFNs expression in currently studied bats species.

Bat Species Type I IFN Type III IFN References
Australian Black Flying Fox
(Pteropus alecto)
• Constitutively expressed IFNalpha
• Contracted locus
• No upregulation with Tioman virus
• Antagonized by henipavirus
• Induced after viral infection with Tioman virus
• Antagonized by henipavirus
Zhou et al., 2016
Zhou et al., 2011a
Egyptian Fruit Bat (Rousettus aegptiacus) • No constitutive expression observed
• Induced after viral infection
• Extensive expansion of IFNw genes
Not determined Pavlovich et al., 2018
Omatsu et al., 2008
Common vampire bat (Desmodus rotundus) • Induction after polyI:C stimulation
• Induction of selective IFN-stimulated genes
Not determined Sarkis et al., 2018
Daubenton’s bat (Myotis daubentoniid) • Induction of IFN-stimulated genes
• Induction of IFNs by virus and polyI:C
Not determined Holzer et al., 2019