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. 2020 Dec 11;11:591815. doi: 10.3389/fimmu.2020.591815

Figure 2.

Figure 2

The impact of NLRX1 deletion on maintenance of mechanical function during 20 min normoxic perfusion in the isolated hearts of protocols 1 to 5. For all parameters, the change in parameter at T=20 min relative to the value at T= 0 min is depicted. (A) end diastolic pressure (EDP), (B) heart rate (HR), (C) Rate Pressure Product (RPP), (D) maximum contraction rate of left ventricle (+dp/dt), (E) maximum relaxation rate of left ventricle (-dp/dt), and (F) Perfusion pressure (Pperf). DLVP, developed left ventricular pressure. All values represent median ± IQ (n=41 in WT group; n=34 in NLRX1-/- group). *P < 0.05, **P < 0.01 by Mann-Whitney U test.