Table 3.

Enrichment of 10 most highly expressed biological pathways in the CSF of patients with PM.

Pathway number	Pathway name	P-adj value enrichment
1	Innate immune system	3.23E-73
2	Immune system	3.72E-61
3	Complement cascade, Regulation of complement cascade	3.29E-59
4	Hemostasis	7.66E-53
5	Neutrophil degranulation	3.29E-43
6	Scavenging heme from plasma	4.16E-41
7	RHO GTPases activate PKNs (actin dynamics)	1.70E-39
8	Binding and Uptake of Ligands by Scavenger Receptors	2.77E-39
9	Classical antibody-mediated complement activation	1.23E-36
10	Platelet degranulation	7.48E-36