Table 2.
All (N = 38) | RRMS (N = 20) | SPMS (N = 18) | p-value* | |
---|---|---|---|---|
Total Thalamic Lesions | ||||
Count | 1.9 ± 1.5 | 1.3 ± 0.7 | 2.6 ± 1.9 | 0.006 |
Volume, mm3 | 99 ± 182 | 42 ± 46 | 163 ± 248 | 0.01 |
Ovoid Lesions | ||||
Count | 1.6 ± 1.4 | 1 ± 0.6 | 2.3 ± 1.7 | 0.002 |
Volume, mm3 | 74 ± 99 | 32 ± 28 | 113 ± 125 | 0.003 |
Number of subjects | 35 | 17 | 18 | |
Periventricular Lesions | ||||
Count | 0.3 ± 0.5 | 0.3 ± 0.6 | 0.2 ± 0.4 | 0.797 |
Volume, mm3 | 133 ± 187 | 62 ± 50 | 223 ± 265 | 0.678 |
Number of subjects | 9 | 5 | 4 | |
Venular Lesions | ||||
Count | 1.5 ± 1.4 | 1 ± 0.6 | 2.1 ± 1.7 | 0.021 |
Volume, mm3 | 63 ± 77 | 28 ± 24 | 97 ± 96 | 0.006 |
Number of subjects | 32 | 16 | 16 | |
Non-venular Lesions | ||||
Count | 0.4 ± 0.9 | 0.4 ± 0.9 | 0.5 ± 0.8 | 0.343 |
Volume, mm3 | 177 ± 301 | 100 ± 69 | 229 ± 391 | 0.208 |
Number of subjects | 10 | 4 | 6 |
Abbreviations: RRMS = relapsing-remitting multiple sclerosis; SPMS = secondary progressive multiple sclerosis;
for comparisons between RRMS and SPMS subjects; all values are reported as mean ± SD