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. 2020 Dec 11;11:601594. doi: 10.3389/fendo.2020.601594

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Copyright © 2020 Fujita, Atageldiyeva, Takeda, Yanagimachi, Makino and Haneda

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lipid metabolism, ketogenesis, and glycogen content in the liver. Serum concentrations of (A) triglycerides (TG), (B) non-esterified fatty acid (NEFA), (C) 3-OHBA concentrations were shown. (D) Fsn, (E) Acd11, (F) HMGC2 mRNA expressions in the liver. (G) Glycogen content in the liver. Data are presented as means ± SEM. n=6, each group. *p < 0.05, **p < 0.01, *** p < 0.001, ****p < 0.0001. White bars, normal-carbohydrate diet (NC); hatched white bars, low-carbohydrate diet (LC); grey bars, NC+Ipra; hatched gray bars, LC+Ipra. NN: non-diabetic mouse.