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. 2020 Dec 11;10:589112. doi: 10.3389/fonc.2020.589112

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Copyright © 2020 Li, Yu, Shi, Cao, Liu, Hao, Ren, Qin, Huang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression of apoptosis or ER stress-associated genes in UC3 cells with combination treatment. (A) mRNA expression of apoptosis-related genes as determined by qRT-PCR. (B) Western blotting analysis for the expression of Bax and Bak. (C) Western blot analysis for the expression of Bip. (D) mRNA expression of genes related to ER stress was investigated by qRT-PCR. Data were expressed as mean ± SEM of duplicate experiments. The differences among multiple groups were assessed using the Analysis of variance (ANOVA). *p < 0.05 versus control, **p < 0.01 versus control, and ***p < 0.001 versus control.