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. 2020 Dec 11;10:583682. doi: 10.3389/fonc.2020.583682

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Copyright © 2020 Ma, Shi, Qu, Zhang, Wu, Zhao, Zhao and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CricRNA-ACAP2 and miR-21-5p regulate ERK phosphorylation through P-STAT3. (A) The expression of miR-21-5p in HN-9 and SCC-25 is significantly suppressed via transfecting pcDNA3.1-CricRNA-ACAP2. (B) When miR-21-5p was knocked down by siRNA, the expression of CricRNA-ACAP2 was significantly up-regulated. (C) CricRNA-ACAP2 and miR-21-5p regulate ERK phosphorylation throughP-STAT3.