Table 4.
Table of treatments that cause ER stress and result in GRP78 overexpression.
| Treatment | Combination Therapy in GBM | Reference |
|---|---|---|
| Pterostilbene | Radiotherapy | (86) |
| Tubastatin A | TMZ | (87) |
| Recombinant plasminogen kringle 5 (rK5) | – | (88) |
| Chloroquine | TMZ + GRP78 knockdown | (89) |
| Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) | – | (90) |
| Endothelial-monocyte activating polypeptide II (EMAP-II) | – | (91) |
| Asiatic acid | – | (92) |
| Ellagic acid | – | (93) |
| Canavanine treatment under lack of arginine | – | (94) |
| C-150 (Mannich-type curcumin derivative) | – | (95) |
| Gamitrinib with bromodomain and extraterminal (BET)-inhibitors | – | (96) |
| Dihydroartemisinin | – | (97) |
| Lysine demethylase KDM1A inhibitor | – | (98) |
| Withaferin A | – | (99) |
| Tumor treating fields (TTFields) | – | (100, 101) |
| RDC11 (ruthenium derived compound) | – | (15, 102) |
| Terpyridineplatinum (II) complexes | – | (15, 103) |
| 2-deoxy-D-glucose + cisplatin | – | (15, 104) |
| SKI-II (4- ((4-(4-chlorophenyl)-2-thiazolyl)amino)phenol) | TMZ | (15, 105) |
| 5-androstene 3β,17α diol (17α-AED) | – | (15, 106) |
| Berberine | – | (15, 107, 108) |
| Bufalin | – | (15, 109) |
| Copper (Cu) | – | (15, 110) |
| Glucosamine | – | (15, 111) |
| Nelifnavir/atazanavir | – | (10, 15, 112) |
| Minocycline (7-dimethylamino-6-desoxytetracycline Mino); | – | (15, 113) |
| Phenethyl isothiocyanate | – | (114–116) |
| Prenyl-phloroglucinol derivative [2,4-bis (4-fluorophenylacetyl)phloroglucinol] | – | (15, 117) |
| S1 (BH3 mimetics) | – | (15, 118) |
| Schweinfurthin analogs | – | (15, 119) |
| Sulindac sulfide | – | (15, 120) |
| Unsaturated fatty acids | Radiotherapy | (15, 121) |
| Valproate | – | (15, 122, 123) |
| Wogonin | – | (15, 124) |
| Carbamazepine | – | (15, 125) |
| Cyclosporine A | – | (15, 126, 127) |
| Ethanol | – | (15, 128, 129) |
| Lead (Pb acetate) | – | (15, 130, 131) |
| Mercury (HgCl2) | – | (15, 130) |
| Oleyl glucosaminide derivative | – | (15, 132) |
| Sesquiterpene coumarin DAW22 | – | (15, 133) |