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. 2020 Dec 11;11:585804. doi: 10.3389/fgene.2020.585804

Figure 6.

Figure 6

(A) Histogram of estimated drug treatment effect using MGANITE, where the x axis denoted the value of ITE and the y axis denoted the number of patients, ITE = +1 denoted the ITE of patients treated with HDAC or HDAC+IDA, ITE = −1 denoted the ITE of patients treated with other drugs, and ITE = 0 denoted the ITE of two groups of patients: one group of the patients treated with HDAC or HDAC+IDA and another group of the patients treated with other drugs. (B) Histogram of observed drug treatment response where the x axis indicated three scenarios as described in (B) and the y axis denoted the number of patients, the right side in the (B) denoted the number of patients only responding to the HDAC or HDAC+IDA, the middle denoted the number of the patients that responds to both (HDAC or HDAC+IDA) and other drugs or did not respond to both (HDAC or HDAC+IDA) and other drugs, and the left side denoted the number of patients only responding to the other drugs.