Table 5.
Effects of encapsulated L-Lys-HCl and DL-Met supplementation on plasma concentrations of ALT, AST, total protein, urate, urea-N, and TAA at the fourth and eighth week1,2
| Item | Control | 80CLM | 60CLM | P-value |
|---|---|---|---|---|
| Week 4: fed state | ||||
| ALT, U/L | 8.09 ± 0.16b | 8.87 ± 0.31a | 8.68 ± 0.18ab | 0.045 |
| AST, U/L | 149 ± 5.0 | 163 ± 6.0 | 159 ± 4.4 | 0.182 |
| Total protein, μmol/L | 52.7 ± 1.9 | 49.3 ± 2.5 | 56.0 ± 2.2 | 0.120 |
| Urate, μmol/L | 237 ± 22.5 | 224 ± 17.1 | 246 ± 9.6 | 0.657 |
| Urea N, mmol/L | 0.30 ± 0.03 | 0.31 ± 0.03 | 0.35 ± 0.02 | 0.487 |
| TAA, μmol/mL | 9.52 ± 0.68 | 10.41 ± 0.96 | 10.67 ± 0.99 | 0.659 |
| Week 4: fasting state | ||||
| ALT, U/L | 8.21 ± 0.32 | 8.23 ± 0.26 | 9.02 ± 0.69 | 0.386 |
| AST, U/L | 155 ± 8.6 | 150 ± 2.9 | 173 ± 10.0 | 0.126 |
| Total protein, μmol/L | 46.3 ± 1.98 | 48.4 ± 1.2 | 46.2 ± 1.1 | 0.507 |
| Urate, μmol/L | 158 ± 14.0 | 165 ± 26.7 | 152 ± 22.8 | 0.311 |
| Urea N, mmol/L | 0.18 ± 0.03 | 0.19 ± 0.02 | 0.17 ± 0.03 | 0.808 |
| TAA, μmol/mL | 8.93 ± 1.04 | 9.43 ± 0.84 | 8.70 ± 0.53 | 0.822 |
| Week 8: fasting state | ||||
| ALT, U/L | 8.94 ± 0.45 | 8.44 ± 0.39 | 8.83 ± 0.15 | 0.584 |
| AST, U/L | 137 ± 7.0 | 143 ± 7.6 | 154 ± 4.2 | 0.185 |
| Total protein, μmol/L | 52.0 ± 2.2 | 52.0 ± 1.6 | 53.1 ± 2.3 | 0.911 |
| Urate, μmol/L | 187 ± 21.4 | 175 ± 18.6 | 192 ± 31.1 | 0.513 |
| Urea N, mmol/L | 0.34 ± 0.04 | 0.31 ± 0.03 | 0.26 ± 0.02 | 0.214 |
| TAA, μmol/mL | 10.2 ± 1.10 | 11.6 ± 1.00 | 9.8 ± 1.28 | 0.311 |
1Basal diet supplemented with encapsulated L-lys HCL and DL-met at 60% (60 CLM) or 80% (80CLM) of the control levels.
2Data were presented as the mean ± SD (n = 10).
a,bMeans with different superscripts within the same line differ significantly, P < 0.05.