Table 2.
Characteristics of vitamin-D-deficient and -sufficient patients prior to liver transplantation.
| All Patients | |||
|---|---|---|---|
| Deficient (20 ng/mL<) | Sufficient (≥20 ng/mL) | p Value | |
| Characteristics | |||
| Age >60 years, Number (%) | 93 (37.1) | 108 (51.7) | <0.01 |
| Sex, Number (%) | 0.37 | ||
| Male | 173 (68.9) | 135 (64.6) | |
| Female | 78 (31.1) | 74 (35.4) | |
| Body mass index, kg/m2, Median (IQR) | 28.7 (24.7–34.1) | 28.6 (25.0–33.3) | 0.90 |
| Main liver disease, Number (%) | 0.08 | ||
| HBV/HCV | 37 (14.7) | 49 (23.4) | |
| PBC/PSC/AIH | 40 (15.9) | 34 (16.3) | |
| NASH | 68 (27.1) | 54 (25.8) | |
| Alcohol | 83 (33.1) | 50 (23.9) | |
| Other | 23 (9.2) | 22 (10.5) | |
| Hepatocellular carcinoma, Number (%) | 64 (25.5) | 77 (36.8) | 0.01 |
| Diabetes mellitus, Number (%) | 70 (27.9) | 66 (31.6) | 0.41 |
| Alcohol consumption, Number (%) | 83 (33.1) | 50 (23.9) | 0.04 |
| MELD-Na score, Median (IQR) | 22 (16–29) | 16 (10–24) | <0.01 |
| Albumin, g/dL, Median (IQR) | 3.0 (2.6–3.5) | 3.2 (2.8–3.7) | 0.04 |
| 25(OH)D, Pre-transplant, ng/mL, Median (IQR) | 12.9 (9.1–16.5) | 27.0 (23.1–32.9) | <0.01 |
| 25(OH)D, Post-transplant, ng/mL, Median (IQR) | 22.1 (14.4–29.0) | 27.1 (20.3–35.5) | 0.32 |
| Crossmatch for T and B cell, Number (%) | 0.24 | ||
| T cell: −/B cell: − | 154 (61.4) | 129 (61.7) | |
| T cell: +/B cell: − | 16 (6.4) | 9 (4.3) | |
| T cell: −/B cell: + | 47 (18.7) | 51 (24.4) | |
| T cell: +/B cell: + | 34 (13.5) | 20 (9.6) | |
IQR: interquartile range; HBV: hepatitis B virus; HCV: hepatitis C virus; PBC: primary biliary cirrhosis; PSC: primary sclerosing cholangitis; AIH: autoimmune hepatitis; NASH: non-alcoholic steatohepatitis; MELD-Na: model for end-stage liver disease; 25(OH)D: 25-hydroxy vitamin D.