Table 4.
Comparison of patient characteristics among different vitamin D supplementation statuses.
| All Patients (N = 528) | |||||
|---|---|---|---|---|---|
| Characteristics | No Supplementation N = 131 |
Pre N = 47 |
Post N = 41 |
Pre/Post N = 309 |
p Value |
| Age >60 years, Number (%) | 65 (49.6) | 18 (38.3) | 14 (34.1) | 138 (44.7) | 0.27 |
| Sex, Number (%) | 0.03 | ||||
| Male | 98 (74.8) | 29 (61.7) | 31 (75.6) | 191 (61.8) | |
| Female | 33 (25.2) | 18 (38.3) | 10 (24.4) | 118 (38.2) | |
| Body mass index, kg/m2, Median (IQR) | 28.7 (24.7–33.8) | 28.5 (22.7–33.1) | 29.0 (25.5–33.3) | 28.7 (24.9–34.0) | 0.98 |
| Main liver disease, Number (%) | 0.12 | ||||
| HBV/HCV | 35 (26.7) | 11 (23.4) | 5 (12.2) | 52 (16.8) | |
| PBC/PSC/AIH | 15 (11.5) | 8 (17.0) | 3 (7.3) | 59 (19.1) | |
| NASH | 32 (24.4) | 11 (23.4) | 14 (34.1) | 80 (25.9) | |
| Alcohol | 38 (29.0) | 14 (29.8) | 11 (26.8) | 90 (29.1) | |
| Other | 11 (8.4) | 3 (6.4) | 8 (19.5) | 28 (9.1) | |
| Hepatocellular carcinoma, Number (%) | 44 (33.6) | 15 (31.9) | 11 (26.8) | 88 (28.5) | 0.70 |
| Diabetes mellitus, Number (%) | 40 (30.5) | 17 (36.2) | 9 (22.0) | 87 (28.2) | 0.49 |
| Alcohol consumption, Number (%) | 38 (29.0) | 14 (29.8) | 11 (26.8) | 90 (29.1) | 0.99 |
| MELD-Na score, Median (IQR) | 19 (13–28) | 18 (11–27) | 22 (15–28) | 19 (14–28) | 0.82 |
| Albumin, g/dL, Median (IQR) | 3.0 (2.6–3.5) | 3.1 (2.8–3.5) | 3.10 (2.4–3.8) | 3.2 (2.7–3.6) | 0.88 |
| 25(OH)D, Pre-transplant, ng/mL, Median (IQR) |
18.1 (11.9–24.4) | 14.3 (9.2–22.6) | 17.65 (10.5–21.5) | 20.2 (13.8–28.4) | <0.01 |
| 25(OH)D, Post-transplant, ng/mL, Median (IQR) |
23.6 (19.4–33.6) | 23.2 (13.1–29.3) | 18.9 (11.4–23.9) | 25.5 (18.2–34.1) | 0.36 |
| Crossmatch for T and B cell, Number (%) | 0.12 | ||||
| T cell: −/B cell: − | 83 (63.4) | 26 (55.3) | 32 (78.0) | 180 (58.3) | |
| T cell: +/B cell: − | 7 (5.3) | 2 (4.3) | 2 (4.9) | 19 (6.1) | |
| T cell: −/B cell: + | 30 (22.9) | 15 (31.9) | 7 (17.1) | 66 (21.4) | |
| T cell: +/B cell: + | 11 (8.4) | 4 (8.5) | 0 (0.0) | 44 (14.2) | |
IQR: interquartile range; HBV: hepatitis B virus; HCV: hepatitis C virus; PBC: primary biliary cirrhosis; PSC: primary sclerosing cholangitis; AIH: autoimmune hepatitis; NASH: non-alcoholic steatohepatitis; MELD-Na: model for end-stage liver disease; 25(OH)D: 25-hydroxy vitamin D.