Table 3.
Survival times of F98 glioma-bearing rats after neutron irradiation.
| Group | n a | Survival Time | %ILS b | ||
|---|---|---|---|---|---|
| Mean ± SD | Median | Range | Median | ||
| Control | 6 | 26.5 ± 1.0 | 26.5 | 25−28 | |
| Irradiated | 5 | 28.2 ± 1.8 | 28 | 26−30 | |
| BADB controls | 5 | 27.8 ± 0.8 | 28 | 27−29 | 5.7% |
| i.v. BPA | 6 | 34.3 ± 1.4 | 34 | 33−36 | 28.3% |
| BADB | 8 | 31.6 ± 2.1 | 31 * | 29−35 | 17.0% |
| BADB and i.v. BPA | 7 | 38.0 ± 1.4 | 38 ** | 36−40 | 43.4% |
a Number of animals. b The percentage of increased lifespan (%ILS) was defined relative to the mean survival times of untreated controls. * i.v. BPA is significantly better than BADB in the median survival time (MST). (p < 0.05 by log-rank test). ** BABD and i.v. BPA is significantly better than i.v. BPA in the MST. (p < 0.05 by log-rank test).