Figure 4.
The effects of Siraitia grosvenorii residual extract (NHGR) on the secretion of Th1 and Th2 cytokines by cultured splenocytes. The concentrations of (a) IL-4, (b) IL-5, (c) IL-13, and (d) IFN-γ in the cell culture supernatant were determined. The cells were maintained for 48 h at a density of 1 × 105 cells/well in 96-well plates using anti-CD3 antibody-coating. Data is showed as the means ± SEM (n = 7). ### p < 0.001 compared with NC; *** p < 0.001 compared with Dermatophagoides farinae extract (DfE)-treated atopic dermatitis mice.