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Effect of Siraitia grosvenorii residual extract (NHGR) on histamine secretion from MC/9 mast cells. (a) Cell viability and (b) histamine secretion. MC/9 cells (2 × 105 cells/mL) were treated with NHGR (25–100 µg/mL) and compound 48/80 (25 µg/mL) for 30 min. Data is showed as means ± SEM (n = 3). ### p < 0.001 versus vehicle; * p < 0.05 and ** p < 0.01 versus compound 48/80-treated control.
