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. 2020 Nov 29;10(12):1614. doi: 10.3390/biom10121614

Figure 5.

Figure 5

Characterization of hiPSC-ECs. Endothelial cells after differentiation from hiPSCs express endothelial markers (e.g., VE-cadherin, Angiopoietin 1-Ang1) and exert potent angiogenic capacity (they form tubule-like structures on Matrigel and spheres in endothelial sprouting assay). hiPSC-ECs properly respond to proinflammatory cytokines (the increase in ICAM-1 (intercellular adhesion molecule 1) expression is evident by flow cytometry analysis) and shear stress.