Figure 2.

Prolonged exposure to 100 nM of either cortisol (A) or dexamethasone (B) does not influence the rate of telomere shortening observed during passaging of human fibroblasts. Telomere length was determined at early, middle, and late passage (0, 24, and 51 days of treatment, respectively). Each time point included 6 biological replicates for the vehicle and cortisol group and 5 biological replicates for the dexamethasone group. Relative telomere lengths were normalized and are shown as percent of the early passage cells. Error bars represent one standard error above and below the mean.