Table 2.
Baseline characteristics, procedural outcomes and adverse events of the included studies for small common bile dust stones.
| Author | Comparison | Study Design |
No. of Patients |
Diameter of Stones (mm) Mean ± SD or Mean (Range) | Balloon Size, mm |
Procedure Time, min |
ML Use % (No.) |
Successful Stone Removal in the 1st Session % (No.) |
Overall Uccessful Stone Removal % (No.) |
Overall AEs % (No.) |
Bleeding % (No.) |
Perforation % (No.) |
PEP % (No.) |
Cholangitis % (No.) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EST vs. EPBD | ||||||||||||||
| Bergman | EST | RCT | 101 | 9 (4–27) |
NA | 12.9% (13) | 91.1% (92) | 91.1% (92) | 11.9% (12) | 4% (4) | 1% (1) | 6.9% (7) | 0% (0) | |
| EPBD | RCT | 101 | 10 (3–36) |
8 | NA | 30.7% (31) | 80.2% (81) | 89.1% (90) | 8.9% (9) | 0% (0) | 2% (2) | 6.9% (7) | 0% (0) | |
| Ochi | EST | RCT | 55 | 8.8 ± 4.2 | NA | 3.7% (2) | 94.4% (51) | 98.1% (54) | 5.6% (3) | 0% (0) | 1.8% (1) | 3.6% (2) | 0% (0) | |
| EPBD | RCT | 55 | 8.1 ± 3.4 | 8 | NA | 13.7% (7) | 78.4% (40) | 92.7% (51) | 0% (0) | 0% (0) | 0% (0) | 0% (0) | 0% (0) | |
| Arnold | EST | RCT | 30 | 10 ± 4.7 | 17 ± 12 | NA | 100% (30) | 100% (30) | 16.7% (5) | 6.7% (2) | 0% (0) | 10% (3) | 0% (0) | |
| EPBD | RCT | 30 | 7 ± 3.5 | 8 | 29 ± 15 | NA | 76.7% (23) | 100% (30) | 30% (9) | 0% (0) | 0% (0) | 20% (6) | 10% (3) | |
| Yasuda | EST | RCT | 35 | 12.3 (5–24) |
NA | 25.7% (9) | 100% (35) | 100% (35) | 8.6% (3) | 2.9% (1) | 0% (0) | 5.7% (2) | 0% (0) | |
| EPBD | RCT | 35 | 12.4 (4–24) |
8 | NA | 48.6% (17) | 100% (35) | 100% (35) | 5.7% (2) | 0% (0) | 0% (0) | 5.7% (2) | 0% (0) | |
| Natsui | EST | RCT | 70 | 9.7 (3–17) |
NA | 38.6% (27) | 70% (49) | 98.6% (69) | 11.4% (8) | 2.9% (2) | 0% (0) | 4.3% (3) | 4.3% (3) | |
| EPBD | RCT | 70 | 9.2 (3–22) |
8 | NA | 41.4% (29) | 58.6% (41) | 92.9% (65) | 8.6% (6) | 0% (0) | 0% (0) | 5.7% (4) | 2.9% (2) | |
| Fujita | EST | RCT | 144 | 7.3 ± 3.4 | NA | 11.8% (17) | 78.5% (113) | 100% (144) | 12.5% (18) | 1.4% (2) | 0% (0) | 2.8% (4) | 8.3% (12) | |
| EPBD | RCT | 138 | 7 ± 3.1 | 4-8 | NA | 14.5% (20) | 76.1% (105) | 99.3% (137) | 14.5% (20) | 0% (0) | 0% (0) | 10.9% (15) | 3.6% (5) | |
| Vlavianos | EST | RCT | 99 | NA | NA | NA | 63.6% (63) | 86.9% (86) | 2% (2) | 0% (0) | 0% (0) | 1% (1) | 1% (1) | |
| EPBD | RCT | 103 | NA | 10 | NA | NA | 63.1% (65) | 87.4% (90) | 6.8% (7) | 0% (0) | 0% (0) | 4.9% (5) | 1.9% (2) | |
| Disario | EST | RCT | 120 | 5 (0.5–14) |
42 ± 19 | NA | 92.5% (111) | NA | 3.3% (4) | 0% (0) | 0.8% (1) | 0.8% (1) | 1.7% (2) | |
| EPBD | RCT | 117 | 6 (0.5–10) |
≤8 | 47 ± 25 | NA | 88% (103) | NA | 17.9% (21) | 0% (0) | 0% (0) | 15.4% (18) | 2.6% (3) | |
| Takezawa | EST | RCT | 45 | 11 (3–27) |
37.2 ± 12.4 | 31.1% (14) | NA | 100% (45) | 0% (0) | 0% (0) | 0% (0) | 0% (0) | 0% (0) | |
| EPBD | RCT | 46 | 10 (1–35) |
8 | 37.4 ± 13 | 34.8% (16) | NA | 100% (46) | 0% (0) | 0% (0) | 0% (0) | 0% (0) | 0% (0) | |
| Watanabe | EST | RCT | 90 | 7.7 ± 2.9 | NA | 64.4% (58) | 57.8% (52) | 95.6% (86) | 3.3% (3) | 1.1% (1) | 0% (0) | 2.2% (2) | 0% (0) | |
| EPBD | RCT | 90 | 8.1 ± 3.2 | 8 | NA | 84.4% (76) | 72.2% (65) | 86.7% (78) | 13.3% (12) | 0% (0) | 0% (0) | 10% (9) | 3.3% (3) | |
| Seo | EST | RCT | 70 | 7.6 ± 3.1 | NA | 8.6% (6) | 91.4% (64) | 100% (70) | 11.4% (8) | 2.9% (2) | 1.4% (1) | 7.1% (5) | 0% (0) | |
| EPBD | RCT | 62 | 7.2 ± 2.1 | 6-10 | NA | 8.1% (5) | 91.9% (57) | 98.4% (61) | 8.1% (5) | 0% (0) | 0% (0) | 8.1% (5) | 0% (0) | |
| EST vs. ESBD | ||||||||||||||
| Ishii | EST | NRCT | 114 | 5.1 ± 2.9 | 31.6 ± 16.8 | 16.7% (19) | 64.9% (74) | 100% (114) | 15.8% (18) | 9.6% (11) | 1.8% (2) | 2.6% (3) | 1.8% (2) | |
| ESBD | NRCT | 321 | 5.6 ± 3 | 8-10 | 25.8 ± 18.8 | 7.8% (25) | 87.2% (280) | 100% (321) | 4.4% (14) | 1.2% (4) | 0.3% (1) | 1.9% (6) | 0.9% (3) | |