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. 2020 Nov 24;10(12):1594. doi: 10.3390/biom10121594

Table 4.

Multiple comparisons in contrast analysis. Post hoc analysis of selected oxidative stress markers in NHDF cells exposed to different concentrations of lactones 13 (SC—starting concentration, MTC—minimal toxic concentration). Statistical significance was set at p < 0.05. Statistically significant values are bolded.

pSC vs. MTC SC MTC
Lactone 1 Lactone
2
Lactone 3 p1 vs. 2 p1 vs. 3 p2 vs. 3 p1 vs. 2 p1 vs. 3 p2 vs. 3
GST (IU/g protein) <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 0.337 <0.001 <0.001
CAT (IU/g protein) <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
GPx (IU/g protein) <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
SOD (Nu/mg protein) <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
MnSOD (NU/mg protein) <0.001 <0.001 0.407 <0.001 <0.001 <0.001 <0.001 <0.001 0.872
CuZnSOD (NU/mg protein) <0.001 <0.01 <0.01 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
TAC (μmol/g protein) <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001
TOS (μmol/g protein) <0.001 <0.001 <0.001 <0.001 <0.001 0.955 0.502 <0.001 <0.001
MDA (μmol/g protein) <0.001 <0.01 <0.001 <0.001 <0.001 <0.05 <0.001 <0.001 <0.001

pSC vs. MTC for lactone 1—SC values compared with MTC; pSC vs. MTC for Lactone 2—SC values compared with MTC; pSC vs. MTC for Lactone 3—SC values compared with MTC. Column SC shows comparisons between SC values for all three lactones. Column MTC shows comparisons between MTC values of all three lactones.