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Multi-subunit replicative DNA pols. Artistic representations were made based on crystal and cryo-EM structures and models of human primase-pol α [58], yeast pol ε [65,67], yeast pol δ [60], yeast pol ζ [66]. Two latter structures were determined with a truncated third subunit (Table 1), Pol 32, without the C-terminal part, and thus, this part is missing from our drawings. Fe-S cluster (
) is present in each of the four pol complexes.
